NovAseptic® Mixers Offer a complete Solution for Mixing Throughout the Process Line

NovAseptic® Mixers offer a complete solution for mixing throughout the process line and are designed for a wide variety of mixing applications in the pharmaceutical and biotechnology industries. The product range includes severa mixer models, so you can find the right mixer for your process and scale.

Robust Design
NovAseptic® mixers are engineered for optimal performance, reliability, durability and ease of maintenance. The desing and development of each component is focused on aseptic design and based on more than 20 years of experience.
Magnetically Coupled
One of the significant advantages of the magnetic drive is that it enables the total integrity of the tank. No shaft is led through the tank wall which could cause leakage and challenge the integrity of the vessel and its contents.
Bottom Mounted
Magnetically-driven mixers have other advantages which are not related to integrity. Dismantling a NovAseptic mixer is easy, wheras a top driven mixer ofter requires a mechanical lifting device. NovAseptic mixers also have the ability to mix enen when the vessel is almost empty, because the mixer is nearly flush with the botton ot the vessel.
Focus on Aseptic Design
Each NovAseptic mixer complies with the most stringent cleanability and sterilizability requirements. All models are completely cleanable and sterilizable-in-place (CIP/SIP)


General Mixing
There are two NovAseptic Mixermodels for gerneral mixing and suspensions.
1). The GMP mixer is the standard model, and is top-of-the-line when it comes to the most critical applications in your process steps that have high demands on cleanability and SIP. The GMP mixer is clean running and is suitable for general mixing, heat transfer and shear sensitive appliations.
2). For upstream processes, the USM mixeris a perfect option. This mixer is a superior alternative to top-mounted moxers in upstream mixing applications. The USM moxer creates medium high-shear forces and transfers much more energy into the tank than the GMP mixer, and is ideal for mixing difficult powders into a liquid.
High Shear Mixing
Two models of NovAseptic Mixers are avilable for high-shear applications involving insluble media such as emulsions, dissolving, or solids that need to be wetted or downsized.
1). The HS mixer is installed into a tank and is used for volumes up to 1,500L (shear rates from 20,000s-1).
2). the HSI moxer is an inline version of the HS mixer, developed for inline powder additions and for blending or particle size reduction. This unit had shear trates from 20,000s-1 and can transfer product between two tanks.
Multiple Mixer Combinations
For certain applications, diferent moxers can be combined tin order to achieve the desired result. For example, an HG micer createds the high shear forces needed to creeate an emulsion, while the GMP mixer is used to break the vortex and create additional agitation and balance in the tank. A variety of powerful results can be achieved this way, such as controlling vortex to prevent foaming, increaded agitation, etc.
Optimizing Your Mixing Process
Enhanced performance, repeatability and the ability to clean- and steam-in-place are all critical considerations when spedifying and aseptic mixing process. These features are built-in with the NovAseptic mixer product range.
Millipore can help you design your process to optimize your mixing steps. Our fully equipped Pre-Validation Center includes the capability to perform live representative tests on your product or process. This center offers several sizes and types of test vessels - sized up to 5,000 L with steam are possible. Together with our experienced mixing specialists you can verify and optimize your aseptic mixing process with the powerful toolbox of NovAseptic Mixers, making it easy to find the right mix for your processing requirements.

Production and Quality Control
NovAseptic Mixers are manufactured in accordance with best practices in quality and undergo a quality control program prior to delivery.The quality control program includes a number of checkpoints to ensure that the mixer parts comply with the highest quality standard, including: 1) Batch number is identified, and quantity is verified against the puchase order. 2) All parts in contact with media are marked with individual ID numbers for full traceability. 3) Measurements are verified against the corresponding drawing. 4) The surface finish is measured with a Perthometer to ensure that the Ra value corresponds to the specification.
A Certificate of Quality is supplied for each mixer part and is delivered with the product.
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